Synchrotron FTIR and XRF imaging of liver cirrhosis

A French group has recently published an interesting report on the analysis of cirrhotic liver tissue. At the Synchrotron Soleil, near Paris in France, scientists combined synchrotron Fourier transform infrared (FTIR) microspectroscopy and synchrotron micro-X-ray fluorescence (XRF) on the same tissue section. They found from FTIR that hepatocytes within cirrhotic nodules have quite highly concentrated esters and sugars, and in the same area, phosphorus and iron were detected by XRF. Also the research team studied their inhomogeneity. For more information, see the paper, "In situ chemical composition analysis of cirrhosis by combining synchrotron-FTIR and synchrotron X-ray fluorescence microspectroscopies on the same tissue section", F. Le Naour et al., Anal. Chem., Just Accepted Manuscipt. Publication Date (Web): 3 Nov 2012.